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What are ingredients of Cernos Gel, Androgel?



Cernos Gel and AndroGel are both topical testosterone replacement therapies used to treat testosterone deficiency (hypogonadism) in men. Their primary active ingredients of Cernos Gel is testosterone in the form of a topical gel.

Ingredients of Cernos Gel and AndroGel

Active Ingredient:

  • Testosterone (usually 1% or 2% concentration, depending on the formulation)

Inactive (Excipients) Ingredients:

These ingredients help in absorption, stabilization, and ease of application:

  • Isopropyl Myristate – Enhances skin penetration of testosterone.
  • Carbomer 980 or 934 – Used as a gelling agent.
  • Ethanol (Alcohol 95-100%) – Acts as a solvent and helps testosterone absorption.
  • Purified Water – Helps in the formulation of the gel.
  • Sodium Hydroxide – Used to adjust the pH of the gel.

The main difference between different brands (such as AndroGel and Cernos Gel) may be the concentration of testosterone and slight variations in inactive ingredients. However, the core function and absorption mechanism remain the same.

Uses of Cernos Gel and AndroGel

Cernos Gel and AndroGel are both topical testosterone replacement therapies used to treat testosterone deficiency (hypogonadism) in men. They help restore normal testosterone levels in the body, improving various symptoms associated with low testosterone.

Medical Uses:

  1. Testosterone Replacement Therapy (TRT) – Used for men with primary or secondary hypogonadism, where the body produces insufficient testosterone.
  2. Improving Symptoms of Low Testosterone, such as:
    • Low energy levels and fatigue
    • Reduced muscle mass and strength
    • Decreased libido and erectile dysfunction
    • Depression, mood swings, and irritability
    • Difficulty concentrating (brain fog)
    • Increased body fat
    • Osteoporosis (weakened bones)
  3. Delayed Puberty in Boys (Off-label use) – Sometimes prescribed for adolescent males with delayed puberty due to low testosterone production.

How to Use Cernos Gel and AndroGel:

  • Application Area: Apply to clean, dry, and intact skin on the shoulders, upper arms, or abdomen (depending on the brand).
  • Dosage: Typically, one daily application of 5g (delivering 50mg testosterone), but dosage may vary based on medical advice.
  • Absorption Time: Allow the gel to dry for 5–10 minutes before dressing.
  • Avoid Washing the Area: Wait at least 2–6 hours before showering or swimming.
  • Prevent Skin Transfer: Avoid direct skin contact with others (especially women and children) for a few hours after applying the gel.

Precautions & Side Effects:

Consultation Required: Should only be used under medical supervision with regular monitoring of testosterone levels.

Side Effects: Skin irritation, increased red blood cell count, acne, hair loss, mood changes, or prostate enlargement.

Safety Precautions: Do not apply to the genitals or broken skin, and always wash hands after use.